EndNote automatically saves references as you add them to your library so you do not need to save your library each time you exit the program. However, it is advisable to save a back up library in a separate location (such as to a USB) so that you don’t lose all your work if you encounter issues with the program or your computer.
Do not use the Save a Copy option in EndNote as this can lead to unnecessary complications with multiple libraries and data files being created.
It is recommended that you use the compressed library option when creating a back up as it zips your .enl and .Data folder into a single file.
If you work on multiple computers (e.g. home, work, uni, laptop), the Library syncing feature in EndNote allows you to synchronise the references in your library between different computers and your EndNote Online account. See Library syncing in the EndNote 20 extras guide for instructions on setting up Library sync.