EndNote automatically saves references as you add them to your library, so you do not need to save the library each time you close the program. However, it is a good idea to create a backup copy of your library in a separate location, such as a USB drive. This helps protect your work in case something goes wrong with the program or your computer.
Important: Do not use the “Save a Copy” option in EndNote. This can cause problems by creating multiple libraries and data folders.
If you use multiple computers (for example, at home, work, or university), you can use Library Syncing to keep your EndNote library up to date across all devices and your EndNote Online account. To learn how to set up syncing, see the Library syncing section in the EndNote Extras Guide.